N-(3-Amino­bicyclo­[2.2.1]heptan-2-yl)-4-methyl­benzene­sulfonamide

نویسندگان

  • Alaa A.-M. Abdel-Aziz
  • Adel S. El-Azab
  • Magda A. El-Sherbeny
  • Seik Weng Ng
  • Edward R. T. Tiekink
چکیده

In the title compound, C(14)H(20)N(2)O(2)S, the sulfonamide O atoms lie to one side of the benzene ring and the amino-bicyclo-hepta-nyl to the other side [C(ar)-S-N-C torsion angle = -57.93 (11)°; ar = aromatic]. An intra-molecular N-H⋯N hydrogen bond is formed. In the crystal, a supra-molecular chain is formed along the b axis via N-H⋯O and N-H⋯N hydrogen bonds.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

[(1S,2S,3R,4R)-3-Hydr­oxy-4,7,7-tri­methyl­bicyclo­[2.2.1]heptan-2-yl]methyl[(E)-3-(trimethyl­silyl)prop-2-enyl]selen­onium bromide

The title compound, a seleno-nium bromide, C(17)H(33)OSeSi(+)·Br(-), was obtained from the reaction of enanti-omerically pure 4,7,7-trimethyl-2-methyl-selanylbicyclo-[2.2.1]heptan-3-ol and (3-bromopropen-yl)trimethyl-silane in acetone. Due to the chiral bicyclic substituent, the crystal structure is not centrosymmetric and has no symmetry plane, with four chiral C atoms in the cation. The asymm...

متن کامل

Crystal structures of two (±)-exo-N-isobornyl­acetamides

The title compounds consist of a bornane skeleton with attached acetamide, C12H21NO (±)-(1) {systematic name: (±)-N-[(1RS,2RS,4RS)-1,7,7-tri-methylbi-cyclo-[2.2.1]heptan-2-yl]acetamide}, and chloro-acetamide, C12H20ClNO (±)-(2) {systematic name: (±)-2-chloro-N-[(1RS,2RS,4RS)-1,7,7-tri-methylbi-cyclo-[2.2.1]heptan-2-yl]-acetamide}, functionalities to the 2-exo-position. The crystal structure of ...

متن کامل

Synthesis, characterization and pharmacological evaluation of substituted phenoxy acetamide derivatives

A novel series of 2-(substituted phenoxy)-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)acetamide and N-(2-bromocyclohexyl)-2-(substituted phenoxy)acetamide derivatives having cyclohexyl nucleus as common in both types were synthesized and assessed for their antiinflammatory activity by a carrageenan induced rat paw oedema method, analgesic activity by Eddy’s hot plate method and antipyretic acti...

متن کامل

Selective activation of cannabinoid CB2 receptors suppresses hyperalgesia evoked by intradermal capsaicin.

The present studies were conducted to test the hypothesis that activation of peripheral cannabinoid CB(2) receptors would suppress hyperalgesia evoked by intradermal administration of capsaicin, the pungent ingredient in hot chili peppers. The CB(2)-selective cannabinoid agonist (2-iodo-5-nitro-phenyl)-[1-(1-methyl-piperidin-2-ylmethyl)-1H-indol-3-yl]-methanone (AM1241) (33, 330 microg/kg i.p.)...

متن کامل

A novel role of cannabinoids: implication in the fever induced by bacterial lipopolysaccharide.

There is continuing interest in elucidating the actions of drugs of abuse on the immune system and on infection. The present study investigated the effects of the cannabinoid (CB) receptor agonist aminoalkylindole, (+)-WIN 55,212-2 [(4,5-dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1ij]quinolin-6-one], on fever produced after injection of lipopolysaccharide...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 68  شماره 

صفحات  -

تاریخ انتشار 2012